The Role of e-NOS in Chronic Cholestasis-Induced Liver and Renal Injury in Rats: The Effect of N-Acetyl Cysteine

Figure 2

(a) (Group C): enlargement of the portal region and bridging fibrosis present in Group B. Enlargement of the portal region was present in Group C, but no bridging fibrosis was present (H&E, ×200). (b) Rat liver e-NOS expression for each week: no staining (0), low (1), moderate (2), and strong (3). (c) Weak cytoplasmic expression of e-NOS in hepatocytes (eNOS, ×200). (d) (Group B) and (e) (Group C): hepatocyte cytoplasmic expression of e-NOS was weaker in Group C than in Group B (eNOS, ×200). (f) (Group B) and (g) (Group C): the necrotic area in Group B was more intense than in Group C (H&E, ×200). (h) (Group B) and (i) (Group C): the necrotic area in Group B was more intense than in Group C (H&E, ×200).

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