Clinical Study

Adalimumab Treatment in Biologically Naïve Crohn’s Disease: Relationship with Ectopic MUC5AC Expression and Endoscopic Improvement

Table 1

Patients' Baseline Characteristics ( ).

Sex (Male/Female)10/5
Age at diagnosis32.1 (19–52)
median (range) (years)
Age at start of the therapy37.2 (20–64)
median (range) (years)
Disease duration5.7 (0.1–21)
median (range) (years)
Extent of disease
 L1 (%)3 (20.0%)
 L2 (%)7 (46.7%)
 L3 (%)5 (33.3%)
Perianal disease (%)6 (40.0%)
Previous surgical resection (%)3 (20.0%)
Concomitant medication
 Predonisolone5
 5-Aminosalicylates12
 Immunosuppresants (AZA)4
 GMA5
 Enteral nutrition4
 Anti-TNFa0

AZA: azathioprine; GMA: granulocyte and monocyte adsorptive apheresis; L1: Ileum; L2: Colon; L3: Ileocolon.
aPrevious use of infliximab or biologic.