Rab27b Is a Potential Predictor for Metastasis and Prognosis in Colorectal Cancer

Table 2

Univariate and multivariate analysis of prognostic factors in 113 CRC patients for overall survival.

	Univariate analysis			Multivariate analysis
	HR		95% CI	HR		95% CI
Rab27b expression
High versus low	2.18	0.010^*	1.204–3.937	2.25	0.041^*	1.032–4.889
Gender
Male versus female	1.47	0.239	0.773–2.810
Age (years)
≥60 versus <60	1.14	0.681	0.607–2.146
Tumor size (cm)
≥5 versus <5	1.23	0.497	0.672–2.267
Tumor location
Colon versus rectum versus ileocecal junction	1.46	0.150	0.872–2.461
Histological type
Adenocarcinoma versus nonadenocarcinoma	2.37	0.233	0.574–9.778
Tumor differentiation
Well and moderate versus poor	0.19	0.001^*	0.097–0.377	0.17	0.001^*	0.072–0.378
Serum CEA level (ng/mL)
≥15 versus <15	2.43	0.028^*	1.101–5.342	1.62	0.275	0.681–3.862
Lymph node metastasis
Positive versus negative	1.43	0.233	0.794–2.578
Distant metastasis
Positive versus negative	4.40	0.005^*	1.559–12.407	4.46	0.066	0.908–21.917
TNM stage
Stage I versus stage II versus stage III versus stage IV	1.75	0.002^*	1.226–2.502	1.12	0.683	0.647–1.942

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