Fistuloclysis Improves Liver Function and Nutritional Status in Patients with High-Output Upper Enteric Fistula

Table 4

Changes from baseline to day 28 for each variable in the fistuloclysis subgroups.

Variables	Group 1 (𝑛=11)	Group 2 (𝑛=16)	Group 3 (𝑛=8)	𝑃 value
TB (𝜇mol/L)	13.8±4.1	24.3±8.9	18.4±5.6	𝟎.𝟎𝟏𝟏^∗
DB (𝜇mol/L)	10.1±3.2	14.1±5.0	13.2±4.8	𝟎.𝟎𝟒𝟎^∗
IB (𝜇mol/L)	3.7±0.8	9.5±3.6	4.3±1.2	<𝟎.𝟎𝟎𝟏^∗
ALT (U/L)	10.5±2.5	4.4±1.7	10.3±2.8	<𝟎.𝟎𝟎𝟏^∗
ALP (U/L)	77.4±24.9	111.9±32.7	102.6±31.7	𝟎.𝟎𝟐𝟐^∗
GGT (U/L)	144.2±50.8	164.2±58.5	158.3±60.3	0.330
TP (g/L)	17.8±6.2	25.7±10.8	21.3±9.8	𝟎.𝟎𝟎𝟓^∗
Alb (g/L)	7.5±2.3	14.3±5.4	9.4±3.2	𝟎.𝟎𝟐𝟎^∗
WBC (10^9/L)	2.5±1.1	2.7±1.1	2.6±1.3	0.884
CRP (mg/L)	2.1±0.7	2.8±0.8	2.4±0.7	0.120
Fistula output (mL/day)	755.4±160.2	830.3±231.5	770.0±215.6	0.232

Group 1: patients with jejunal-ileal fistula; Group 2: patients with biliary fistula; Group 3: patients with duodenal fistula. EF: enteric fistula; TB: total bilirubin; DB: direct bilirubin; IB: indirect bilirubin; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GGT:𝛾-glutamyltransferase; TP: total protein; Alb: albumin; WBC: white blood cells; CRP: C-reactive protein. Data were presented as mean ± SD. 𝑃 value < 0.05 was deemed significant.