The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study

Table 3

Serum CA-125 level differed in patients with Budd-Chiari syndrome (mean ± SD).

	Ascites		Liver function^*
	Yes ()	No ()	Normal ()	Abnormal ()
CA-125 (U/mL)	242.7 ± 300.1	20.7 ± 12.3	86.9 ± 174.2	307.69 ± 444.7
	10.4		−4.14
	0.000		0.000
	Complicated with hepatocellular carcinoma^##		Albumin^**
	Yes ()	No ()	Normal ()	Abnormal ()
CA-125 (U/mL)	184.4 ± 423.3	145.2 ± 229.9	97.7 ± 201.1	285.0 ± 303.0
	0.80		−6.08
	0.423		0.000

Data in the table not well represented by a normal distribution by Kolmogorov-Smirnov test and tested by Wilcoxon W rank test.
^*Serum alanine transaminase and (or) aspartate aminotransferase higher than upper limit of normal range (>40 U/L), regarded as abnormal function of liver.
^**Serum albumin lower than lower limit of normal range (<35 g/L), regarded as decreased serum albumin.
^##Budd-Chiari syndrome complicated with hepatocellular carcinoma: indicated by pathological biopsy results or a nodule with typical imaging features (hypervascular nodule with washout during the portal venous phase of dynamic enhanced scan) and a serum alpha fetal protein level greater than 400 ng/L.