Review Article

Role of TLR4  rs4986790A>G and rs4986791C>T Polymorphisms in the Risk of Inflammatory Bowel Disease

Table 1

MAF of the SNPs in different ethnic groups from the HapMap population.

Ethnicityrs4986790A>Grs4986791C>T

CEU
 AllelesA:GC:T
 MAF0.0330.033
CHB
 AllelesA:AC:C
 MAF00
YRI
 AllelesA:GC:C
 MAF0.0330
JPT
 AllelesA:AC:C
 MAF00
JPT + CHB
 AllelesA:AC:C
 MAF00

CEU: 30 trios of Utah residents of Northern and Western European ancestry; CHB: 45 unrelated Han Chinese individuals from Beijing, China; YRI: 30 adult-and-both-parents Yoruba trios from Ibadan, Nigeria; JPT: 44 unrelated Japanese individuals from Tokyo, Japan; JPT + CHB: combined panel of Japanese in Tokyo, Japan, and Han Chinese in Beijing, China; MAF: minimum minor allele frequency; SNP: single nucleotide polymorphism.