Procoagulatory State in Inflammatory Bowel Diseases Is Promoted by Impaired Intestinal Barrier Function

Figure 1

Circulating LPS and TLR2 are increased in IBD and correlate with each other in UC. Concentrations of LPS and TLR2 were measured in the sera of IBD (both UC and CD) patients and healthy controls (CONT). (a) LPS serum levels in CONT, UC, and CD patients (left panel) and CD locations according to Montreal classification (right panel). (b) TLR2 serum levels in CONT, UC, and CD patients (left panel) and CD locations according to Montreal classification (right panel). (c) Correlation between circulating levels of LPS and TLR2 in IBD patients. (d) Correlation between circulating levels of LPS and TLR2 in UC (left panel) and CD (right panel) patients. Horizontal bars in (a) and (b) represent median and interquartile range. Statistical analysis was performed by means of Mann-Whitney Test and Spearman Correlation Test. was considered statistically significant.

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