Procoagulatory State in Inflammatory Bowel Diseases Is Promoted by Impaired Intestinal Barrier Function

Figure 2

TLR4 serum correlates with circulating LPS in IBD patients. Concentrations of LPS and TLR4 were measured in the sera of IBD (both UC and CD) patients. (a) TLR4 serum levels in UC and CD patients (left panel) and CD locations according to Montreal classification (right panel). (b) Correlation between circulating levels of LPS and TLR4 in IBD patients. (c) Correlation between circulating levels of LPS and TLR4 in UC (left panel), CD (central panel) patients, and CD patients with colonic and ileocolonic involvement (L2 + L3 according to Montreal classification) (right panel). Horizontal bars in (a) represent median and interquartile range. Statistical analysis was performed by means of Spearman Correlation Test. was considered statistically significant.

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