Procoagulatory State in Inflammatory Bowel Diseases Is Promoted by Impaired Intestinal Barrier Function

Figure 3

Circulating LPS correlates with biochemical but not clinical activity in IBD patients. Concentrations of LPS, TLR2, TLR4, and CRP were measured in the sera of IBD (both UC and CD) patients. Clinical activity of UC and CD was evaluated using Mayo score and Harvey-Bradshaw Index. (a) Correlation between CRP serum levels and circulating LPS, TLR2, and TLR4 in IBD patients. (b) Correlation between Mayo score and circulating LPS, TLR2, and TLR4 in UC patients. (c) Correlation between Harvey-Bradshaw Index and circulating LPS, TLR2, and TLR4 in CD patients. Statistical analysis was performed by means of Spearman Correlation Test. was considered statistically significant.

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