Procoagulatory State in Inflammatory Bowel Diseases Is Promoted by Impaired Intestinal Barrier Function

Figure 6

Circulating LPS correlates with markers of activated coagulation in CD patients with colonic involvement. Concentrations of LPS and levels of D-Dimer and prothrombin fragment were measured in the sera and plasma, respectively, of CD patients. (a) Correlation between D-Dimer plasma levels and serum LPS in all CD patients (left panel), CD patients with exclusive ileal involvement (L1 according to Montreal classification) (central panel), and CD patients with colonic involvement (L2 + L3 according to Montreal classification). (b) Correlation between prothrombin fragment and circulating LPS in all CD patients (left panel), CD patients with exclusive ileal involvement (L1 according to Montreal classification) (central panel), and CD patients with colonic involvement (L2 + L3 according to Montreal classification). Statistical analysis was performed by means of Spearman Correlation Test. was considered statistically significant.

(a)  

(b)