Site-Specific Immunomodulator: A Novel Treatment for Crohn’s Disease

Figure 1

SSI QBECO- and LPS-induced cytokine release in THP-1 cells. THP-1 cells were activated overnight with PMA, then stimulated with diluted SSI QBECO (1 : 2500–1 : 20 dilution, (a)-(b)) or LPS (0.01–10 g/mL) for 18 hrs. Supernatants were removed and TNF- ((a), (c)) or IL-1 ((b), (d)) was assessed by specific ELISA. Data are means ± standard deviation of triplicate assessments from one of three similar experiments.

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