| | | | | | | Montreal Classification | | | | | | | | | Patient | Sex | Date of birth | Age at diagnosis of CD (yrs) | Disease prior to SSI (yrs) | Age at diagnosis of CD | Location of CD | Behavior | Previous resection | Prior CD therapy | Past use of TNF-α blocker | Medication refractoriness prior to SSI | Symptoms at initiation of SSI | Symptom severity at initiation of SSI | Medications at initiation of SSI |
| | 1 | M | 11-May-83 | 23 | 4 | A2 | L3 | B1 | 0 | Prednisone, Imuran | No | Steroid dependant, Imuran | Pain, diarrhea, and weight loss | Severe | Imuran, Prednisone |
| | 2 | F | 07-Jan-85 | 24 | 2 | A2 | L1 | B3 | 0 | Prednisone, antibiotics | No | Steroid dependant | Pain, diarrhea, RLQ abscess, and weight loss | Moderate | Prednisone |
| | 3 | F | 01-Dec-77 | 4 | 30 | A1 | L2 | B2 | 1 | Prednisone, Remicade | Yes | Steroid dependant, Remicade | Pain, diarrhea, and anemia | Severe | Prednisone |
| | 4 | F | 29-Jan-88 | 21 | 3 | A2 | L3 | B3p | 1 | Prednisone, Imuran, Remicade | Yes | Imuran | Pain, diarrhea, and fistulae | Severe | Imuran |
| | 5 | F | 05-Sep-73 | 35 | 3 | A2 | L3 | B3p (RV fistula) | 0 | 5ASA | No | 5ASA | Pain, diarrhea | Moderate | 5ASA |
| | 6 | F | 13-Sep-78 | 20 | 13 | A2 | L2 | B1 | 0 | Prednisone, Purinethol, 5ASA, Entocort | No | Purinethol, 5ASA, Entocort | Pain, diarrhea | Moderate | none |
| | 7 | F | 22-Sep-73 | 24 | 15 | A2 | L2 | B1 | 0 | Prednisone, Remicade, 5ASA | Yes | Remicade, 5ASA | Pain, diarrhea | Moderate | 5ASA |
| | 8 | M | 04-Sep-85 | 24 | 3 | A2 | L2 | B1 | 0 | Prednisone, 5ASA | No | 5ASA | Pain, diarrhea, and weight loss | Severe | none |
| | 9 | M | 01-Oct-76 | 19 | 16 | A2 | L3 + L4 | B3p | 1 | Prednisone, Remicade, 5ASA | Yes | Steroid dependant, Remicade, 5ASA | Pain, diarrhea, and fistulae | Severe | Prednisone |
| | 10 | F | 07-Nov-67 | 45 | 0.5 | A3 | L3 | B3p | 0 | Prednisone, Imuran, 5ASA | Yes | Steroid dependant, Imuran, 5ASA | Pain, diarrhea | Moderate | Prednisone, 5ASA |
|
|
Patient demographic criteria were based on the Montreal Classification of CD [10]: Age at diagnosis of CD: A1: ≤16 years, A2: 17–40 years, A3: >40 years; Location of Crohn’s disease: L1: terminal ileum, L2: colon, L3: ileocolon, L4: upper GI, L1 + L4: terminal ileum + upper GI, L2 + L4: colon + upper GI, and L3 + L4; ileocolon + upper GI; and Behavior: B1: nonstricturing, nonpenetrating, B2: stricturing, B3: penetrating, B1p: nonstricturing, nonpenetrating + perianal, B2p: stricturing + perianal, and B3p: penetrating + perianal.
|
