Table 2: Pathohistological results of patients with locally advanced rectal cancer receiving capecitabine/irinotecan +/− cetuximab based chemoradiotherapy as preoperative treatment.

Capecitabine/irinotecan ()Capecitabine/irinotecan + cetuximab () value

ypT downstaging, (%)
ypT0 7 (19)4 (8)
ypT1 5 (14)1 (2)
ypT211 (30)18 (37)
ypT312 (32)24 (49)
ypT42 (5)2 (4)
Chi square0.11
ypN−23 (62)36 (73)
ypN+14 (38)13 (27)
Fisher’s exact test0.35

R0 resection, (%)
36 (97)48 (98)
Fisher’s exact test1.00

Pathologic complete remission ypT0 pN0, (%)
7 (19)4 (8)
Fisher’s exact test0.19

T-downstaging (ypT0-2, pN0), (%)
9 (24)21 (43)
Fisher’s exact test0.11