Optimization of Deep Sedation with Spontaneous Respiration for Therapeutic Endoscopy Combining Propofol and Bispectral Index Monitoring

Figure 2

Maintenance of sedation. (1) Continuous drip infusion was performed using an automatic infusion pump (atom syringe pump S-1235; Atom Medical Corp.). (2) When the patient moved, a bolus injection of 1.0 mL propofol was repeated every min until suitable sedation was obtained. The infusion rate was increased by 5 mL/h. (3) Continuous drip infusion was stopped temporarily under the following conditions: SpO₂ < 90%, systolic blood pressure (SBP) < 80 mmHg, or BIS score < 60 (≥5 s). (4) Following recovery, the infusion rate was decreased by 5 mL/h.