Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?

Figure 1

Representative mechanisms of lncRNAs implication in gastrointestinal cancer cell proliferation. (a) Promotion of gastric and colorectal cancer cell proliferation by H19. (b) Inhibition of gastric and pancreatic cell proliferation by GAS5; CRC: colorectal cancer, GC: gastric cancer, HCC: hepatocellular carcinoma, and PC: pancreatic cancer.

(a)

(b)