Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?

Figure 2

Representative mechanisms of lncRNAs implication in gastrointestinal cancer invasion and metastasis. (a) Promotion of gastric and colorectal cancer invasion and metastasis by HOTAIR. (b) Inhibition of hepatocellular carcinoma cell invasion by Dreh; CRC: colorectal cancer, GC: gastric cancer, HCC: hepatocellular carcinoma, and PC: pancreatic cancer.

(a)

(b)