Review Article
Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?
Table 2
An overview of the biomarker potential of lncRNAs for hepatocellular and pancreatic cancer.
| | lncRNA | Cancer type | Sample | Expression | Clinical application | Reference |
| | HULC | HCC | Tissue/plasma | Up | Diagnosis/unfavorable prognosis | [123] |
| | uc003wbd | HCC | Serum | Up | Diagnosis | [124] |
| | AF085935 | HCC | Serum | Up | Diagnosis | [124] |
| | HEIE | HCC | Tissue | Up | Unfavorable prognosis | [51] |
| | MVIH | HCC | Tissue | Up | Unfavorable prognosis | [128] |
| | URCH | HCC | Tissue | Up | Unfavorable prognosis | [129] |
| | lncRNA-ATB | HCC | Tissue | Up | Unfavorable prognosis | [130] |
| | HOTTIP | HCC | Tissue | Up | Unfavorable prognosis | [131] |
| | hDREH | HCC | Tissue | Down | Favorable prognosis | [76] |
| | LET | HCC | Tissue | Down | Favorable prognosis | [125] |
| | GAS5 | HCC | Tissue | Down | Favorable prognosis | [133] |
| | MALAT1 | PDAC | FFPE tissues | Up | Unfavorable prognosis | [134, 135] |
| | ENST00000480739 | PDAC | Tissue | Down | Favorable prognosis | [3] |
| | BC008363 | PDAC | Tissue | Down | Favorable prognosis | [138] |
| | HOTAIR | HCC | Tissue | Up | Unfavorable prognosis | [127] | | Pancreatic cancer | Tissue | Up | Unfavorable prognosis | [136] |
| | PVT1 | HCC | Tissue | Up | Unfavorable prognosis | [132] | | PDAC | Tissue | Up | Unfavorable prognosis | [137] |
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