Review Article
Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets?
Table 3
An overview of the biomarker potential of lncRNAs for esophageal cancer.
| lncRNA | Cancer type | Sample | Expression | Clinical application | Reference |
| HOTAIR | ESCC | Tissue | Up | Unfavorable prognosis | [148] |
| LOC285194 | ESCC | Tissue | Down | Favorable prognosis and prediction of response to chemotherapy | [158] |
| POU3F3 | ESCC | Plasma | Up | Diagnosis | [143] |
| UCA1 | ESCC | Tissue | Up | Unfavorable prognosis | [151] |
| SPRY4-IT1 | ESCC | Tissue | Up | Unfavorable prognosis | [152] |
| PCAT-1 | ESCC | Tissue | Up | Unfavorable prognosis | [153] |
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