Clinical Study

Outcomes and Risk Factors Associated with Clostridium difficile Diarrhea in Hospitalized Adult Patients

Table 1

Baseline characteristics of patients with Clostridium difficile colitis and controls with hospital-acquired diarrhea of other causes.

VariableCDI group ()Control group ()

Median age, years (range)54.4 (18.0–91.0)53.3 (16.0–88.0)
Male 36 (48.0)36 (48.0)
Unit in which hospitalized
 Medical ward60 (80.0)60 (80.0)
 Surgical ward15 (20.0)15 (20.0)
Relevant comorbidities1
 Diabetes mellitus13 (17.3)15 (20.0)
 Chronic renal disease10 (13.3)11 (14.6)
 Solid organ cancer23 (30.6)8 (10.6)
 Hematological cancer10 (13.3)10 (13.3)
Solid organ transplant5 (6.6)5 (6.6)
Bone narrow transplant3 (4.0)5 (6.6)
Deaths214 (18.6)13 (17.3)
Median length of hospital stay (days) 50.333.4
Median duration of antibiotic use (days) 14.515.8
Number of antibiotics used
 None4 (5.3)12 (16.0)
 One16 (21.3)16 (21.3)
 Two12 (16.0)13 (17.3)
 Three20 (26.6)12 (16.0)
 Four or more23 (30.6)22 (29.3)

Data presented as (%) unless otherwise indicated. CDI: Clostridium difficile infection. 1Most prevalent comorbidities among cases and controls (). 2Death from all causes.