Research Article
Characteristics and Prognostic Significance of Preoperative Magnetic Resonance Imaging-Assessed Circumferential Margin in Rectal Cancer
Table 1
The relationship between mrCRM status and clinicopathological characteristics.
| | Frequency | mrCRM status | value | | | | Clear mrCRM | Involved mrCRM | | Number | % | Number | % | Number | % |
| Total | — | — | 171 | 84.2 | 32 | 15.8 | | Age, years | | | | | | | | 65 | 113 | 55.7 | 94 | 83.2 | 19 | 16.8 | 0.645 | 65 | 90 | 44.3 | 77 | 85.6 | 13 | 14.4 | Sex | | | | | | | | Male | 104 | 51.2 | 87 | 83.7 | 17 | 16.3 | 0.815 | Female | 99 | 48.8 | 84 | 84.8 | 15 | 15.2 | Preoperative CEA | | | | | | | | 5 ng/L | 147 | 72.4 | 124 | 84.4 | 23 | 15.6 | 0.941 | 5 ng/L | 56 | 27.6 | 47 | 83.9 | 9 | 16.1 | mrT classification | | | | | | | | mrT1-2 | 30 | 14.8 | 30 | 100 | 0 | 0 | 0.01 | mrT3 | 173 | 85.2 | 141 | 81.5 | 32 | 18.5 | mrN classification | | | | | | | | mrN(−) | 114 | 56.2 | 102 | 89.5 | 12 | 10.5 | 0.02 | mrN(+) | 89 | 43.8 | 69 | 77.5 | 20 | 22.5 | Location of closest mrCRM in bowel wall | | | | | | | | Anterior | 107 | 52.7 | 83 | 77.6 | 24 | 22.4 | 0.023 | Lateral | 84 | 41.4 | 77 | 91.7 | 7 | 8.3 | Posterior | 12 | 5.9 | 11 | 91.7 | 1 | 8.3 | Peritoneal reflex relationship | | | | | | | | Above | 39 | 19.2 | 35 | 89.7 | 4 | 10.3 | 0.294 | Below | 164 | 80.8 | 136 | 82.9 | 28 | 17.1 | Tumor distance from anal verge | | | | | | | | 5 cm | 85 | 41.9 | 78 | 91.8 | 7 | 8.2 | 0.012 | 5 cm | 11.8 | 58.1 | 93 | 78.8 | 25 | 21.2 | pT classification | | | | | | | | pT1-2 | 60 | 29.6 | 58 | 96.7 | 2 | 3.3 | 0.002 | pT3-4 | 143 | 70.4 | 113 | 79.0 | 30 | 21.0 | pN classification | | | | | | | | pN0 | 113 | 55.7 | 106 | 93.8 | 7 | 6.2 | 0.0001 | pN1-2 | 90 | 44.3 | 65 | 72.2 | 25 | 27.8 | TNM stage | | | | | | | | Stage I | 48 | 23.6 | 46 | 95.8 | 2 | 4.2 | 0.0001 | Stage II | 65 | 32.0 | 60 | 92.3 | 5 | 7.7 | Stage III | 90 | 44.3 | 65 | 72.2 | 25 | 27.8 | pCRM status | | | | | | | | pCRM(−) | 189 | 93.1 | 164 | 86.8 | 25 | 13.2 | 0.0002 | pCRM(+) | 14 | 6.9 | 7 | 50.0 | 7 | 50.0 | Tumor grade | | | | | | | | Low-medium | 170 | 83.7 | 146 | 85.9 | 24 | 14.1 | 0.144 | High | 33 | 16.3 | 25 | 75.8 | 8 | 24.2 |
|
|
mrCRM, MRI-assessed circumferential margin; CEA, carcinoembryonic antigen; pCRM, pathological circumferential margin.
|