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Gastroenterology Research and Practice
Volume 2015 (2015), Article ID 434039, 6 pages
http://dx.doi.org/10.1155/2015/434039
Clinical Study

The Prevalence of Gastric Intestinal Metaplasia and Distribution of Helicobacter pylori Infection, Atrophy, Dysplasia, and Cancer in Its Subtypes

1Medical Faculty, Department of Gastroenterology, Yuzuncu Yil University, 65080 Van, Turkey
2Medical Faculty, Department of Internal Medicine, Yuzuncu Yil University, 65080 Van, Turkey
3Medical Faculty, Department of Pathology, Yuzuncu Yil University, 65080 Van, Turkey
4Dr. Ersin Arslan Public Hospital, Department of Gastroenterology, Gaziantep, Turkey

Received 10 January 2015; Revised 23 February 2015; Accepted 12 March 2015

Academic Editor: Jithinraj Edakkanambeth Varayil

Copyright © 2015 Sehmus Olmez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. Gastric intestinal metaplasia (IM) is frequently encountered and is considered a precursor of gastric adenocarcinoma. In the Van region of Turkey, gastric adenocarcinoma incidence is high but the prevalence of gastric IM is not known. Helicobacter pylori (H. pylori) infection is a main factor leading to atrophy, IM, and cancer development in the stomach. The aim of the current study was to investigate the prevalence of IM and its subtypes and the prevalence of H. pylori infection, atrophy, dysplasia, and cancer in gastric IM subtypes. Materials and Methods. This retrospective study was conducted on 560 IM among the 4050 consecutive patients who were undergoing esophagogastroduodenoscopy (EGD) with biopsy between June 2010 and October 2014. Clinical records and endoscopic and histopathologic reports of patients with IM were analyzed. Results. The prevalence of gastric IM was 13.8%. The prevalence of incomplete IM was statistically significantly higher than complete IM. Type III IM was the most frequent subtype. Conclusions. Gastric IM is a common finding in patients undergoing EGD with biopsy in this region. High prevalence of incomplete type IM, especially type III, can be associated with the high prevalence of gastric cancer in our region.