Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways

<div>Immunohistochemical staining of Bcl-xL, Bax, Caspase-3, Bad, PTEN, pAKT, and Western blot test on selected proteins (Caspase-3/cleaved, Bcl-XL, and Bax). Upper: immunohistochemical staining (×400). Left: Western blot. Groups: A: NS, B: 5-FU, C: 0.5 mg/kg, D: 1.0 mg/kg, and E: 1.5 mg/kg.</div>

Gastroenterology Research and Practice

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Figure 5

Figure 5: Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways 

Figure 5 | Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways 