Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT Pathways

Table 1

Tumor volumes, inhibitory rate, and apoptotic rate in xenograft tumor.

Group		Tumor volume (mm^3)	Inhibitory rates (%)	Apoptosis rate (%)
NS	6	120.99 ± 39.69	—	3.46 ± 0.24
5-FU	6	36.81 ± 23.99	69.6	3.14 ± 0.56
BL	6	65.78 ± 26.14	45.6	11.93 ± 5.21
BM	6	52.99 ± 13.45	56.2	13.07 ± 4.36
BH	6	50.17 ± 28.12	58.5	9.61 ± 7.17

Note. BL: Bufalin low dose group; BM: Bufalin median dose group; BH: Bufalin high dose group.
compared with NS group; and compared with 5-FU group.