Diabetes and Insulin Therapy, but Not Metformin, Are Related to Hepatocellular Cancer Risk

Table 1

Distribution of 224 cases of hepatocellular carcinoma (HCC) and 389 controls according to selected factors (Italy, 2005–2012).

	HCC cases		Controls
		(%)		%
Age (years)
60	44	(19.6)	154	(39.6)
60–69	81	(36.2)	104	(26.7)
70	99	(44.3)	131	(33.7)
Sex
Male	162	(72.3)	240	(61.7)
Female	62	(27.7)	149	(38.3)
Tobacco smoking^a
Never smoker	86	(39.1)	208	(54.2)
Ever smoker	134	(60.9)	176	(45.8)
Hepatitis^a,b
No	65	(29.0)	269	(97.1)
Yes	159	(71.0)	11	(2.9)

^aThe sum does not add up to the total because of some missing values.
^bHepatitis includes hepatitis B and/or C.