The Diagnostic Value of Brush Cytology Alone and in Combination with Tumor Markers in Pancreaticobiliary Strictures

Table 2

Diagnostic performance of CA19-9, CA 125, brush cytology, and combination of three methods.

	Marker value	Sensitivity %	Specificity %	PPV %	NPV %	Accuracy %
Brush cytology		62.4	97.7	96.7	70.9	79.4
CA-19.9 (U/mL)	72.5	73.8	79.5	79.4	73.9	76.5
CA-125 (ng/mL)	17.5	74.4	61.5	68.1	68.6	68.2
Combination of the three methods^*		94.1	54.5	80	82.8	80.6

PPV: positive predictive value, NPV: negative predictive value.
If at least one of the following is positive: brush cytology, CA-19.9, or CA-125.