Research Article
Association between Virulence Factors and TRAF1/4-1BB/Bcl-xL Expression in Gastric Mucosa Infected with Helicobacter pylori
Table 2
Samples positive or negative for cagA, vacAs1, or vacAm1 stratified according to TRAF1, 4-1BB, and Bcl-xL expression.
| | Group | TRAF1 | 4-1BB | Bcl-xL | | ↑ | — | ↑ | — | ↑ | — |
| | cagA+/vacAs1+/vacAm1+ | 50 (64.9) | 15 (21.1) | 50 (66.7) | 15 (20.5) | 47 (59.4) | 18 (26.1) | | cagA+/vacAs1+/vacAm1− | 6 (7.8) | 10 (14.1) | 7 (9.3) | 9 (12.3) | 4 (5.1) | 12 (17.4) | | cagA+/vacAs1−/vacAm1+ | 3 (3.9) | 12 (16.9) | 3 (4.0) | 12 (16.4) | 7 (8.9) | 8 (11.6) | | cagA+/vacAs1−/vacAm1− | 3 (3.9) | 10 (14.1) | 3 (4.0) | 10 (13.7) | 3 (3.8) | 10 (14.5) | | cagA−/vacAs1+/vacAm1+ | 3 (3.9) | 6 (8.5) | 5 (6.7) | 4 (5.5) | 5 (6.3) | 4 (5.8) | | cagA−/vacAs1+/vacAm1− | 5 (6.5) | 8 (11.3) | 1 (1.3) | 12 (16.4) | 3 (3.8) | 10 (14.5) | | cagA−/vacAs1−/vacAm1+ | 2 (2.6) | 5 (7.0) | 3 (4.0) | 4 (5.5) | 4 (5.1) | 3 (4.3) | | cagA−/vacAs1−/vacAm1− | 5 (6.5) | 5 (7.0) | 3 (4.0) | 7 (9.6) | 6 (7.6) | 4 (5.8) | | cagA+ | 62 (80.5) | 47 (66.2) | 63 (84.0) | 46 (63.0) | 61 (77.2) | 48 (69.6) | | cagA− | 15 (19.5) | 24 (33.8) | 12 (16.0) | 27 (37.0) | 18 (22.8) | 21 (30.4) | | vacAs1+ | 64 (83.1) | 39 (54.9) | 63 (84.0) | 40 (54.8) | 59 (74.7) | 44 (63.8) | | vacAs1− | 13 (16.9) | 32 (45.1) | 12 (16.0) | 33 (45.2) | 20 (25.3) | 25 (36.2) | | vacAm1+ | 58 (75.3) | 38 (53.5) | 61 (81.3) | 35 (47.9) | 63 (79.7) | 33 (47.8) | | vacAm1− | 19 (24.7) | 33 (46.5) | 14 (18.7) | 38 (52.1) | 16 (20.3) | 36 (52.2) |
| | Total | 77 (100.0) | 71 (100.0) | 75 (100.0) | 73 (100.0) | 79 (100.0) | 69 (100.0) |
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↑, upregulated; —, unaltered. compared with unaltered group. Data are presented as the number of cases and percentage (%).
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