Primary Antimicrobial Susceptibility Changes in Children with Helicobacter pylori Infection over 13 Years in Northern Italy

Table 3

Differences in antibiotic resistance.

Antibiotic	MIC interpretative values	Resistance rate	Resistance rate	value
	(μg/mL)	(years 1998-99)	(years 2011-12)
Metronidazole	>16	35 (56%)	15 (33%)	0.014
Clarithromycin	>4	10 (16%)	12 (26%)	0.142
Ampicillin	>4	2 (3%)	0	ns
Tetracyclines	>16	1 (2%)	0	ns
Metronidazole + clarithromycin		5 (8%)	3 (7%)	ns
Total		63/75 (84%)	46/66 (70%)	0.079