Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease
Table 2
The biochemical data for the patients with different liver diseases.
Viral hepatitis (HBV + HCV)
ALD
Biliary tract disease
NAFLD
Other liver diseases
Healthy controls
ALT (U/L)
77.1 (59.0, 100.8)
79.7 (49.6, 128.0)
79.7 (49.6, 128.0)
64.1 (34.2, 120.0)
57.4 (38.5, 85.6)
12.0 (6.0, 23.0)
AST (U/L)
74.9 (59.3, 94.5)
54.9 (34.4, 87.5)
67.3 (44.5, 101.7)
46.2 (26.8, 79.8)
62.0 (43.7, 87.8)
19.0 (14.0, 32.0)
ALP (U/L)
279.4 (241.8, 322.9)
347.4 (260.1, 464.0)
566.0 (438.0, 731.3)**
261.8 (186.5, 367.5)
433.5 (349.3, 538.0)**
163.5 (121.0, 291.0)
Γ-GTP (U/L)
70.4 (55.4, 89.6)
113.6 (70.2, 183.8)
224.1 (146.3, 343.2)**
45.1 (25.7, 79.3)
102.9 (71.9, 147.4)
16.0 (11.0, 32.0)
T-Bil (mg/dL)
1.18 (0.95, 1.46)
1.05 (0.69, 1.62)
2.09 (1.43, 3.05)*
1.19 (0.72, 1.97)
1.41 (1.02, 1.94)
0.8 (0.5, 1.9)
D-Bil (mg/dL)
0.15 (0.10, 0.23)
0.12 (0.05, 0.29)
0.49 (0.22, 1.06)*
0.12 (0.04, 0.33)
0.16 (0.08, 0.31)
0.1 (0.0, 0.1)
TBA (M)
14.57 (10.55, 20.11)
15.67 (8.27, 29.70)
22.64 (12.64, 40.56)
13.04 (6.03, 28.20)
15.60 (9.59, 25.37)
2.8 (1.0, 15.1)
ALB (g/dL)
3.65 (3.49, 3.82)
3.45 (3.16, 3.77)
3.09 (2.86, 3.35)**
3.77 (3.40, 4.18)
3.25 (3.03, 3.47)**
4.8 (4.3, 5.2)
PT (%)
80.9 (76.4, 85.7)
84.2 (75.0, 94.4)
82.3 (74.2, 91.3)
86.5 (75.6, 99.0)
76.3 (70.1, 83.1)
93.0 (71.0, 112.0)
The values in patients with liver disease are the least square geometric mean concentrations with 95% CI. The values in healthy controls are the median with 2.5% point and 97.5% point. < 0.01 and < 0.05 versus viral hepatitis in patients with liver disease.
