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Gastroenterology Research and Practice
Volume 2015, Article ID 723954, 13 pages
Review Article

Assessing of Celiac Disease and Nonceliac Gluten Sensitivity

1Unidad Académica de Ciencias de la Nutrición, Universidad Autónoma de Sinaloa, Avenida Cedros y Calle Sauces, S/N, Fracc. Los Fresnos, 80019 Culiacán, SIN, Mexico
2Programa Regional de Doctorado en Biotecnología, FCQB, Universidad Autónoma de Sinaloa, Ciudad Universitaria, 80040 Culiacán, SIN, Mexico
3Immunology Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia

Received 19 November 2014; Accepted 15 April 2015

Academic Editor: Leticia Moreira

Copyright © 2015 N. Ontiveros et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The publication of papers on the topic of gluten related disorders has substantially increased over the last few years. This has motivated healthcare professionals to pay attention not only to celiac disease and wheat allergy but also to a condition termed nonceliac gluten sensitivity (NCGS). Until now this condition has been diagnosed clinically on the basis of exclusion criteria and clinical response to gluten withdrawal. In addition, recent research in this field has shown that other food components distinct from gluten are implicated in NCGS cases, thereby changing our general understanding of NCGS diagnosis in either individuals on gluten containing diets or those already following a gluten-free diet with no proper diagnostic work-up of celiac disease. With this in mind, the assessment of NCGS will require extensive knowledge of celiac disease manifestations and the laboratory tests commonly performed during diagnosis of celiac disease.