KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?

Table 4

Contingency table for determination of BRAF mutation status using immunostaining.

	BRAF mutation status
	wt	Mutated	Total
BRAF immunohistochemistry status
−	10	0	10
+	0	20	20
Total	10	20	30

Sensitivity = 20/20 = 100%.
Specificity = 10/10 = 100%.