Research Article

Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy

Table 1

Clinical baseline characters of the patients with and without preoperative PBD.

PBD ()No-PBD () value

Mean age (years)59 ± 257 ± 10.494
Male gender28 (59.6%)166 (57.6%)0.803
Hypertension8 (17.0%)50 (17.4%)0.954
Cardiovascular disease1 (2.1%)17 (5.9%)0.487
Diabetes mellitus3 (6.4%)28 (9.8%)0.594
Smoking pack-years (>20)14 (30.4%)94 (32.8%)0.755
White blood cells (×109/L)7.2 ± 0.56.6 ± 0.20.282
Hemoglobin (g/L)121.5 ± 2.7119.6 ± 1.00.476
Platelet count (×109/L)201.3 ± 11.2214.7 ± 5.00.311
Total bilirubin (μmol/L)363.2 ± 18.0136.0 ± 8.40.001
Alanine aminotransferase (U/L)91.1 ± 11.895.7 ± 4.80.715
Aspartate aminotransferase (U/L)73.6 ± 8.081.4 ± 3.70.419
Albumin (g/L)38.3 ± 0.940.7 ± 2.60.710
Prothrombin time (s)12.9 ± 0.212.7 ± 0.10.500
Fibrinogen (g/L)4.1 ± 0.24.3 ± 0.10.250
Carcinoembryonic antigen (ng/mL)3.8 ± 0.45.7 ± 2.10.703
Carbohydrate antigen 125 (U/mL)19.6 ± 3.131.6 ± 6.20.398
Carbohydrate antigen 19-9 (U/mL)1062.5 ± 570.6675.0 ± 203.20.471
Diameter of pancreatic duct (cm)0.6 ± 0.10.6 ± 0.20.772
Tumor diameter (cm)3.5 ± 0.24.3 ± 0.40.414
Diameter of common bile duct (cm)1.6 ± 0.11.7 ± 0.10.460
Blood loss (mL)463.8 ± 52.5475.4 ± 33.50.893
Total expenditure (US dollars)10158.9 ± 1152.58889.1 ± 280.50.129
Pathological diagnosis0.881
 Benign disease2 (4.3%)16 (5.6%)
 Malignant carcinoma45 (95.7%)272 (94.4%)
Nutrient tube placement8 (17.0%)65 (22.6%)0.393
Combined vessel resection1 (2.1%)9 (3.1%)1.000
Hospital stay (days)25210.350

PBD, preoperative biliary drainage.