Association between JAK2 rs4495487 Polymorphism and Risk of Budd-Chiari Syndrome in China
Table 3
Laboratory characteristics at presentation for Budd-Chiari syndrome patients with the JAK2 rs4495487 polymorphism.
rs4495487 genotype
value
value
value
CC
CT
TT
Age (years)
43.53 (30.39–56.67)
44.33 (30.76–57.90)
44.71 (31.48–57.94)
0.934
0.743
0.763
Male (%)
9 (60.00)
38 (46.34)
106 (57.92)
0.197
0.875
0.130
Alanine aminotransferase (U/L)
22.0 (18.0–33.0)
21.0 (16.0–32.0)
21.0 (16.0–29.0)
0.950
0.810
0.940
Aspartate aminotransferase (U/L)
28.0 (22.0–39.0)
29.5 (22.0–41.0)
30.0 (24.0–43.0)
0.725
0.620
0.423
Platelets (109/L)
137.0 (105.0–221.0)
108.0 (75.0–160.0)
93.0 (70.0–133.0)
0.019
0.007
0.530
White blood cell (109/L)
3.43 (2.89–3.88)
3.58 (2.78–4.98)
3.94 (2.97–5.38)
0.538
0.286
0.292
Red blood cell (109/L)
4.63 (3.68–5.63)
4.18 (3.68–4.65)
4.17 (7.72–4.64)
0.699
0.324
0.865
Hemoglobin (g/L)
120.0 (111.0–135.5)
118.5 (102.0–141.0)
120.0 (103.0–134.0)
0.762
0.560
0.478
Carcinoembryonic antigen (ng/mL)
1.74 (0.95–2.97)
1.78 (0.92–2.42)
2.11 (1.32–3.45)
0.049
0.322
0.014
Child-Pugh score
7 (6–13)
6 (5–12)
7 (6–12)
0.171
0.410
0.295
MELD score
9.26 (5.20–12.63)
7.94 (5.08–11.72)
8.80 (5.44–12.32)
0.584
0.890
0.393
Clichy score
5.48 (4.52–6.35)
4.93 (4.31–6.16)
5.24 (4.52–6.26)
0.218
0.910
0.136
Rotterdam score
1.12 (0.19–1.19)
1.11 (0.12–1.19)
1.14 (0.23–1.22)
0.154
0.886
0.079
BCS-TIPS score
4.53 (3.90–5.27)
4.31 (3.74–5.13)
4.40 (3.68–5.17)
0.699
0.513
0.882
Data are medians, with ranges in parentheses. Continuous data are expressed as median (25–75 percentiles) and categorical data as frequencies (percentage). : value genotype comparisons (CC/CT/TT); : for CC versus TT; : value for CC/CT versus TT genotype comparisons. MELD: model for end-stage liver disease; TIPS: transjugular intrahepatic portosystemic shunt.
