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Gastroenterology Research and Practice
Volume 2015, Article ID 810134, 8 pages
http://dx.doi.org/10.1155/2015/810134
Research Article

Clinical and Oncological Value of Preoperative BMI in Gastric Cancer Patients: A Single Center Experience

1Department of Medicine, Surgery and Neurosciences, Unit of General Surgery and Surgical Oncology, University of Siena, Policlinico “Le Scotte”, Viale Bracci, 53100 Siena, Italy
2Department of Medicine, Surgery and Neurosciences, Unit of General and Mini-Invasive Surgery, University of Siena, Policlinico “Le Scotte”, Viale Bracci, 53100 Siena, Italy

Received 29 October 2014; Revised 20 January 2015; Accepted 20 January 2015

Academic Editor: Gianfranco D. Alpini

Copyright © 2015 Costantino Voglino et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. The impact of preoperative BMI on surgical outcomes and long-term survival of gastric cancer patients was investigated in various reports with contrasting results. Materials & Methods. A total of 378 patients who underwent a surgical resection for primary gastric cancer between 1994 and 2011 were retrospectively studied. Patients were stratified according to BMI into a normal group (<25, group A), an overweight group (25–30, group B), and an obesity group (≥30, group C). These 3 groups were compared according to clinical-pathological characteristics, surgical treatment, and long-term survival. Results. No significant correlations between BMI and TNM (2010), UICC stage (2010), Lauren’s histological type, surgical results, lymph node dissection, and postoperative morbidity and mortality were observed. Factors related to higher BMI were male gender , diabetes , and serum blood proteins . A trend to fewer lymph nodes retrieved during gastrectomy with lymphadenectomy in overweight patients (B and C groups) was observed, although not statistically significant. There was no difference in overall survival or disease-specific survival between the three groups. Conclusion. According to our data, BMI should not be considered a significant predictor of postoperative complications or long-term result in gastric cancer patients.