Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management

Table 2

American Joint Committee on Cancer (AJCC). TNM Staging for Intrahepatic Bile Duct Tumors (7th edition, 2010).

Primary tumor (T)
TX	Primary tumor cannot be assessed
T0	No evidence of primary tumor
Tis	Carcinoma in situ (intraductal tumor)
T1	Solitary tumor without vascular invasion
T2a	Solitary tumor with vascular invasion
T2b	Multiple tumors, with or without vascular invasion
T3	Tumor perforating the visceral peritoneum or involving the
	Local extra hepatic structures by direct invasion T4 Tumor with periductal invasion
Regional lymph nodes (N)
NX	Regional lymph nodes cannot be assessed N0 No regional lymph node metastasis
N1	Regional lymph node metastasis present
Distant metastasis (M)
M0	No distant metastasis
M1	Distant metastasis present
Anatomic stage groupings
Stage 0	Tis	N0	M0
Stage I	T1	N0	M0
Stage II	T2	N0	M0
Stage III	T3	N0	M0
Stage IVA	T4	N0	M0
	Any T	N1	M0
Stage IVB	Any T	Any N	M1