From Molecular Classification to Targeted Therapeutics: The Changing Face of Systemic Therapy in Metastatic Gastroesophageal Cancer

Figure 1

(a) Molecular classification of gastric adenocarcinomas. Primary gastric adenocarcinomas () were analyzed in the TCGA project and found to have four main subtypes: CIN (chromosomal instability) 49.8%, GS (genomically stable) 19.6%, MSI (microsatellite instability) 21.7%, and EBV (Epstein-Barr virus), positive 8.8%. Adapted from data in TCGA [18]. (b) Characteristics of molecular subtypes of gastric cancer. Adapted from data in TCGA [18]. The key features of each molecular subtype are listed adjacent to the representation of subtype.

(a)

(b)