Regulators of Actin Dynamics in Gastrointestinal Tract Tumors

Table 1

Expression patterns of actin-binding proteins in gastrointestinal tract tumors.

	Arp2/3	Fascin	N-WASP	WAVE	Cortactin	Abi1–3	Cofilin
ESCC	—	↑ [35]	↑ [42]	—	↑ [67–71]	↓ [95]	↑ [42]
GAC	↑ [24]; ↓ [25, 26]	↑ [36]	—	↓ [53]; ↑ [54]	↓ ↑ [36]; ↑ [72–75]	↓ [95]	(↑) [106]
CRC	↑ [29, 30]	↑ [37]	↓ [44]; [45]	↑ [30]	↑ [76, 78–81]	↓ [95]; ↑ [81, 96, 97]	(↑) [108–111]
HCC	—	↑ [39]	↑ [47]	↑ [57]	↑ [82–85]	—	↓ [112]
PDAC	↑ [31, 32]	↑ [38]	↑ [46]	—	↑ [86, 87]	↑ [98, 99]	↑ [113]

ESCC: esophageal squamous cell carcinoma; GAC: gastric adenocarcinoma; CRC: colorectal carcinoma; HCC: hepatocellular carcinoma; PDAC: pancreatic ductal adenocarcinoma.
In metastases versus primary tumors.