Research Article

The Anti-Inflammatory Activity of a Novel Fused-Cyclopentenone Phosphonate and Its Potential in the Local Treatment of Experimental Colitis

Figure 3

Cleavage of the fluorescent peptide substrate Mca-P-L-A-Q-A-V-Dpa-R-S-S-S-R-NH2 by purified human recombinant TACE in the presence of elevated concentrations of P-5 or doxycycline.