Correlations of Human Epithelial Growth Factor Receptor 2 Overexpression with MUC2, MUC5AC, MUC6, p53, and Clinicopathological Characteristics in Gastric Cancer Patients with Curative Resection

Table 3

Univariate and multivariate analysis of clinicopathological variables for the survival of the patients with gastric carcinoma.

Variables	Relative risk (95% CI)	value
Univariate
TNM stage	5.317 (2.936–9.630)
Tumor size (5 cm <)	2.962 (1.051–8.345)
Depth of invasion (T3-T4)	2.453 (1.649–3.647)
Nodal status (N stage)	3.973 (2.375–6.647)
p53 expression (+)	0.287 (0.080–1.024)
MUC2 expression (+)	1.786 (0.565–5.640)
MUC5AC expression (+)	1.728 (0.488–6.125)
MUC6 expression (+)	1.257 (0.397–3.977)
HER2 overexpression (+)	4.673 (1.690–12.922)
Lauren classification	1.914 (1.099–3.337)
Vascular invasion (+)	12.218 (4.143–36.029)
Lymphatic invasion (+)	17.917 (4.033–79.610)
Neural invasion (+)	5.049 (1.830–13.926)
Multivariate: Cox regressional hazard model
HER2 overexpression (+)	3.394 (1.173–9.819)
Nodal status (N stage)	3.840 (2.278–6.473)