CD44, Sonic Hedgehog, and Gli1 Expression Are Prognostic Biomarkers in Gastric Cancer Patients after Radical Resection

Table 2

Univariate and multivariate analysis for overall survival in gastric cancer after radical resection.

Factors	Univariate regression analysis				Multivariate regression analysis
	value	OR	95% CI	P value	value	OR	95% CI	P value
Age	0.001	0.995	0.589–1.679	0.984
Gender	0.076	0.927	0.540–1.592	0.783
Tumor location	0.052	0.966	0.713–1.307	0.820
Tumor size	10.301	2.957	1.525–5.733	0.001
Histological type	7.097	2.457	1.268–4.760	0.008
Gross type	5.811	2.252	1.164–4.357	0.016
T stage	11.943	3.370	1.692–6.713	0.001
N stage	5.334	2.473	1.147–5.333	0.021
TNM stage	21.978	3.070	1.921–4.906	<0.001	11.856	1.346	1.137–1.594	0.001
CD44 expression	16.049	3.589	1.921–6.706	<0.001
Shh expression	13.707	4.490	2.028–9.945	<0.001
Gli1 expression	28.800	8.927	4.013–19.858	<0.001	9.970	4.247	1.731–10.423	0.002