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Gastroenterology Research and Practice
Volume 2016, Article ID 1619053, 9 pages
Review Article

The Changing Phenotype of Inflammatory Bowel Disease

Department of Medicine and the APC Microbiome Institute, University College Cork, National University of Ireland, Cork, Ireland

Received 8 September 2016; Revised 1 November 2016; Accepted 8 November 2016

Academic Editor: Bjørn Moum

Copyright © 2016 Carthage Moran et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


It is widely known that there have been improvements in patient care and an increased incidence of Inflammatory Bowel Disease (IBD) worldwide in recent decades. However, less well known are the phenotypic changes that have occurred; these are discussed in this review. Namely, we discuss the emergence of obesity in patients with IBD, elderly onset disease, mortality rates, colorectal cancer risk, the burden of medications and comorbidities, and the improvement in surgical treatment with a decrease in surgical rates in recent decades.