Clinical Study

High Dose Ilaprazole/Amoxicillin as First-Line Regimen for Helicobacter pylori Infection in Korea

Table 1

Baseline characteristics of the study population.

CharacteristicsEradication success
Eradication failure 
value

Gender, (%)0.20
 Male15 (65.2)2 (33.3)
 Female8 (34.8)4 (66.7)
Age, years, mean ± SD 47.5 ± 10.649.3 ± 7.10.63
Underlying gastric disease, (%)
 Gastritis21 (91.3)6 (100.0)1.00
 Gastric ulcer1 (4.3)0 (0.0)1.00
 Duodenal ulcer1 (4.3)0 (0.0)1.00
Smoking, (%)
 Current smoker7 (30.4)1 (16.7)0.65
 Ex-smoker5 (21.7)0 (0)0.55
 Never smoker11 (47.9)5 (83.3)0.18
Alcohol, (%)
 Nonalcohol drinker6 (26.1)3 (50.0)0.55
 Social drinker14 (60.9)2 (33.3)0.25
 Heavy drinker3 (13.0)1 (16.7)0.36
Compliance, (%)0.20
 Good23 (100)5 (83.3)
 Bad0 (0)1 (16.7)
Side effect, (%) 3 (13.0)0 (0)1.00

Helicobacter pylori eradication rate was 79.3% based on the intention-to-treat analysis. Drinking fewer than 3 bottles/week, drinking more than 3 bottles/week, and taking less than 80% of all study drugs. The value was derived from Student’s -test for age variable, and the values for the other variables were derived from the chi-square or Fisher’s exact test. SD: standard deviation.