Research Article

The Effects of Infliximab on Laminin, NFκB, and Anti-TNF Expression through Its Effect on Ischemic Liver Tissue

Table 1

Histopathological examination of liver tissue.

GroupHepatocytes degeneration
Median ± SD
Central canal dilatation
Median ± STD
Increase of connective tissue
and edema in the portal area
Median ± SD
Bile duct epithelial degeneration
Median ± SD
Sinusoidal dilation
Median ± SD

C0.00 ± 0.421.00 ± 0.420.00 ± 0.480.00 ± 0.320.00 ± 0.42
ISC3.00 ± 0.474.00 ± 0.423.00 ± 0.322.00 ± 0.323.00 ± 0.42
ISC inf2.00 ± 0.673.00 ± 0.672.00 ± 0.421.00 ± 0.572.00 ± 0.00

In the statistical evaluations performed, significant differences were observed between C and ISC groups in terms of hepatocyte degeneration, central canal dilatation, increase of connective tissue and edema in the portal area, bile duct epithelial degeneration, and sinusoidal dilation according to the Kruskal-Wallis test ().
In the statistical evaluations performed, significant differences were observed between C and ISC inf groups in terms of hepatocyte degeneration, central canal dilatation, increase of connective tissue and edema in the portal area, bile duct epithelial degeneration, and sinusoidal dilation according to the Kruskal-Wallis test ().
In the statistical evaluations performed, significant differences were observed between ISC and ISC inf groups in terms of hepatocyte degeneration, central canal dilatation, increase of connective tissue and edema in the portal area, bile duct epithelial degeneration, and sinusoidal dilation according to the Kruskal-Wallis test ().