Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans

Table 2

Identified hypermethylated genes in colon neoplasia progression.

Genes	Spearman correlation	Adjusted value (false detection rate)	Normal	Tubular adenoma	Tubulovillous adenoma	Tumor
L3MBTL1	0.22	2.93	0.0057	0.002353	0.00784	0.09
NKX6-2	0.08	0.000158	0.0144	0.00375	0.0000	0.12
PREX1	0.16	0.03	0.0057	0.0000	0.121	0.17
TRAF7	0.20	0.000244	0.0000	0.0000	0.0000	0.06
PRDM14	0.24	0.01	0.0000	0.0000	0.0000	0.27
NEFM	0.06	0.04	0.00	0.0000	0.0000	0.14