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Gastroenterology Research and Practice
Volume 2016, Article ID 2349453, 6 pages
http://dx.doi.org/10.1155/2016/2349453
Research Article

miR-203 Expression in Exfoliated Cells of Tongue Coating Represents a Sensitive and Specific Biomarker of Gastroesophageal Reflux Disease

1Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, 110 Ganhe Road, Hongkou, Shanghai 200437, China
2Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China

Received 19 May 2016; Accepted 26 July 2016

Academic Editor: Tetsuro Setoyama

Copyright © 2016 Xiuli Yan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. X. J. Yang, H. M. Jiang, X. H. Hou, and J. Song, “Anxiety and depression in patients with gastroesophageal reflux disease and their effect on quality of life,” World Journal of Gastroenterology, vol. 21, no. 14, pp. 4302–4309, 2015. View at Publisher · View at Google Scholar
  2. J. O. Hayat, S. Gabieta-Somnez, E. Yazaki et al., “Pepsin in saliva for the diagnosis of gastro-oesophageal reflux disease,” Gut, vol. 64, no. 3, pp. 373–380, 2015. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Jiang, X. Liang, Y. Chen et al., “Integrating next-generation sequencing and traditional tongue diagnosis to determine tongue coating microbiome,” Scientific Reports, vol. 2, p. 936, 2012. View at Publisher · View at Google Scholar
  4. Z. M. Sun, J. Zhao, P. Qian et al., “Metabolic markers and microecological characteristics of tongue coating in patients with chronic gastritis,” BMC Complementary and Alternative Medicine, vol. 13, no. 1, p. 227, 2013. View at Publisher · View at Google Scholar
  5. S. Han, Y. Chen, J. Hu, and Z. Ji, “Tongue images and tongue coating microbiome in patients with colorectal cancer,” Microbial Pathogenesis, vol. 77, pp. 1–6, 2014. View at Publisher · View at Google Scholar
  6. N. I. Hornick, J. Huan, B. Doron et al., “Serum Exosome MicroRNA as a minimally-invasive early biomarker of AML,” Scientific Reports, vol. 5, Article ID 11295, 2015. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Zhou, G. Gong, H. Tan et al., “Urinary microRNA-30a-5p is a potential biomarker for ovarian serous adenocarcinoma,” Oncology Reports, vol. 33, no. 6, pp. 2915–2923, 2015. View at Publisher · View at Google Scholar
  8. F. Wang, J. F. Lou, Y. Cao et al., “miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy,” Experimental & Molecular Medicine, vol. 47, article e162, 2015. View at Publisher · View at Google Scholar
  9. J. Zhang, Y. Song, C. Zhang et al., “Circulating MiR-16-5p and MiR-19b-3p as two novel potential biomarkers to indicate progression of gastric cancer,” Theranostics, vol. 5, no. 7, pp. 733–745, 2015. View at Publisher · View at Google Scholar · View at Scopus
  10. B. P. L. Wijnhoven, D. J. Hussey, D. J. Watson, A. Tsykin, C. M. Smith, and M. Z. Michael, “MicroRNA profiling of Barrett's oesophagus and oesophageal adenocarcinoma,” British Journal of Surgery, vol. 97, no. 6, pp. 853–861, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. C. M. Smith, M. Z. Michael, D. I. Watson et al., “Impact of gastro-oesophageal reflux on microRNA expression, location and function,” BMC Gastroenterology, vol. 13, no. 1, article 4, 2013. View at Publisher · View at Google Scholar
  12. P. Bus, P. D. Siersema, R. E. Verbeek, and J. W. P. M. van Baal, “Upregulation of miRNA-143, -145, -192, and -194 in esophageal epithelial cells upon acidic bile salt stimulation,” Diseases of the Esophagus, vol. 27, no. 6, pp. 591–600, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Mallick, S. K. Patnaik, S. Wani, and A. Bansal, “A systematic review of esophageal microRNA markers for diagnosis and monitoring of Barrett's esophagus,” Digestive Diseases and Sciences, vol. 61, no. 4, pp. 1039–1050, 2016. View at Publisher · View at Google Scholar
  14. E. Sonkoly, T. Wei, P. C. J. Janson et al., “MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?” PLoS ONE, vol. 2, no. 7, Article ID e610, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. R. Yi, M. N. Poy, M. Stoffel, and E. Fuchs, “A skin microRNA promotes differentiation by repressing ‘stemness’,” Nature, vol. 452, no. 7184, pp. 225–229, 2008. View at Publisher · View at Google Scholar
  16. X. Zhou, G. Xu, C. Yin, W. Jin, and G. Zhang, “Down-regulation of miR-203 induced by Helicobacter pylori infection promotes the proliferation and invasion of gastric cancer by targeting CASK,” Oncotarget, vol. 5, no. 22, pp. 11631–11640, 2014. View at Google Scholar · View at Scopus
  17. F. Zhang, Z. Yang, M. Cao et al., “MiR-203 suppresses tumor growth and invasion and down-regulates MiR-21 expression through repressing Ran in esophageal cancer,” Cancer Letters, vol. 342, no. 1, pp. 121–129, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. N. Wang, H. Liang, Y. Zhou et al., “miR-203 suppresses the proliferation and migration and promotes the apoptosis of lung cancer cells by targeting SRC,” PLoS ONE, vol. 9, no. 8, Article ID e105570, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Tian, M. Li, J. Ge et al., “MiR-203 is downregulated in laryngeal squamous cell carcinoma and can suppress proliferation and induce apoptosis of tumours,” Tumor Biology, vol. 35, no. 6, pp. 5953–5963, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. X. Zhu, K. Er, C. Mao et al., “miR-203 suppresses tumor growth and angiogenesis by targeting VEGFA in cervical cancer,” Cellular Physiology and Biochemistry, vol. 32, no. 1, pp. 64–73, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Gu, Y. Wang, and X. Wu, “MicroRNA in the pathogenesis and prognosis of esophageal cancer,” Current Pharmaceutical Design, vol. 19, no. 7, pp. 1292–1300, 2013. View at Google Scholar · View at Scopus
  22. O. Slaby, J. Srovnal, L. Radova et al., “Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma,” Carcinogenesis, vol. 36, no. 5, pp. 521–527, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. M. N. Primo, R. O. Bak, B. Schibler, and J. G. Mikkelsen, “Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes,” Cytokine, vol. 60, no. 3, pp. 741–748, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. Z. Yang, L. Zhong, S. Zhong, R. Xian, and B. Yuan, “miR-203 protects microglia mediated brain injury by regulating inflammatory responses via feedback to MyD88 in ischemia,” Molecular Immunology, vol. 65, no. 2, pp. 293–301, 2015. View at Publisher · View at Google Scholar