Dysfunctions in the Mature Dendritic Cells Are Associated with the Presence of Metastases of Colorectal Cancer in the Surrounding Lymph Nodes
Table 2
The correlations between the number of CD83 positive cells in the front of the tumor and in the main mass of the tumor and the clinicopathological parameters.
Number of CD83 positive cells
Parameter
In invasion front
In main mass of tumor
Mean (range)
value (coefficient)
Mean (range)
value (coefficient)
Age
<60
14
5.5 (0–17)
NS
0.2 (0–3)
NS
≥60
57
4.9 (0–16)
1.0 (0–8)
Gender
Male
41
4.9 (0–17)
NS
0.8 (0–8)
NS
Female
30
5.2 (0–16)
0.9 (0–8)
Localization
Colon
40
5.1 (0–16)
NS
1.0 (0–8)
NS
Rectum
31
5.0 (0–17)
0.6 (0–6)
Adenocarcinoma type
Nonmucinous
64
4.9 (0–17)
NS
0.9 (0–8)
NS
Mucinous
7
5.8 (2–12)
0.1 (0-1)
pT stage
1
1
3.0 (3)
NS
2.0 (2)
NS
2
4
4.7 (0–9)
0.7 (0–3)
3
64
5.1 (0–17)
0.8 (0–8)
4
2
3.5 (3-4)
1.0 (0–2)
Lymph node metastasis
Absent
42
4.2 (0–16)
<0.05 (0.278)
0.5 (0–8)
<0.01 (0.308)
Present
29
6.2 (0–17)
1.2 (0–8)
Distant metastasis
Absent
59
5.2 (0–17)
NS
0.9 (0–8)
NS
Present
12
4.4 (0–11)
0.2 (0–2)
Tumor budding
Absent
18
4.3 (0–16)
NS
0.8 (0–8)
NS
Present
53
5.3 (0–17)
0.8 (0–8)
Lymphocytic infiltration
0
11
5.1 (0–15)
NS
1.3 (0–8)
NS
1
33
5.2 (0–17)
0.6 (0–6)
2
20
4.9 (0–16)
1.0 (0–8)
3
7
4.5 (2–9)
0.4 (0–2)
Vascular invasion
Absent
33
4.7 (0–16)
NS
0.6 (0–8)
<0.01 (0.312)
Present
38
5.3 (0–17)
1.0 (0–8)
The statistically significant results were indicated with bold type. NS: statistically nonsignificant.
