Gastroenterology Research and Practice / 2016 / Article / Tab 1

Research Article

Serum Immunoglobulin A (IgA) Level Is a Potential Biomarker Indicating Cirrhosis during Chronic Hepatitis B Infection

Table 1

Demographic and clinical characteristics of the subjects.

Cirrhosis ()Noncirrhosis ()HCs ()

Gender (male/female) 83/2152/1838/170.313
Age (y) 54.0 ± 11.042.5 ± 12.544.8 ± 8.7<0.001
Total protein (g/L)61.1 ± 7.764.1 ± 6.770.5 ± 4.0<0.001
Albumin (g/L) 29.8 ± 5.337.2 ± 6.245.6 ± 3.2<0.001
ALT (U/L) 23.0 (14.0–38.8)125.5 (40.3–301.0)15.0 (11.0–21.0)<0.001
AST (U/L) 36.0 (25.0–58.5)81.5 (45.3–145.8)19.0 (16.0–21.0)<0.001
GGT (U/L)40.5 (20.3–71.0)65.0 (37.8–147.8)18.5 (13.0–26.0)<0.001
INR1.40 ± 0.291.38 ± 0.440.93 ± 0.10<0.001
Creatinine (mmol/L)77.0 (66.0–94.0)67.0 (58.5–81.5)65.0 (55.0–79.0)<0.001
Platelets (×109/L)70.0 (43.0–122.0)167.0 (103.3–202.5)214.0 (180.3–244.0)0.001
Hemoglobin (g/L)101.0 (83.8–120.0)138.0 (123.5–150.5)137.5 (130.0–153.0)<0.001
Blood urea nitrogen (mmol/L) 6.05 (4.50–8.15)4.60 (3.90–5.40)4.90 (4.22–5.60)<0.001
HBsAg-positive () 10470
HBeAg-positive ()6070
HBV-DNA positive ()10470

Data are expressed as , mean ± SD, or median (interquartile range).
ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transferase; INR, international normalized ratio.
, comparison among the three groups.
, compared with noncirrhosis group.
, compared with HCs group.

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