Research Article

Association of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome

Table 4

Plasma nitrite levels (μmol/L) in HRS, cirrhosis, and control groups.

GroupsTotally median (Min–Max)G894T median (Min–Max)T/C 786 median (Min–Max)
GGGTTTTTTCCC

HRS ()39.7 (31.7–73.6)<0.00148.8 (35.3–73.6)39.5 (34.3–42.7)32.8 (31.7–39.4)<0.00141.5 (34.3–73.6)39.5 (32.7–48.8)36 (31.7–46.2)0.058
Cirrhosis ()34.5 (28.6–45.6)35.6 (28.6–45.6)34.5 (34.3–34.7)30.9 (30.0–39.8)0.78036.1 (30.9–45.6)33.0 (28.6–37.6)30.7 (30.0–34.7)0.029
Control ()25.4 (20.2–29.7)25.9 (23.4–29.0)25.1 (23.1–29.7)20.2 (20.2–20.2)0.30725.4 (23.1–29.7)25.4 (20.2–28.1)25.3 (23.6–27.1)0.992

HRS, hepatorenal syndrome; plasma nitrite level (μmol/L).
versus cirrhosis group, versus control group, versus HRS with G894T GG genotype, versus HRS with G894T GT genotype, and versus cirrhosis with T786C TT genotype.