Fecal Microbiota Transplantation Using Upper Gastrointestinal Tract for the Treatment of Refractory or Severe Complicated Clostridium difficile Infection in Elderly Patients in Poor Medical Condition: The First Study in an Asian Country
Table 2
Pre-FMT and post-FMT data of the patients.
Patient number
Age
Sex
K-P scale
Mental status
Cognition
Index infection
CCIs
Number of diarrhea per day
WBC count (cell/mcL)
Cr (mg/dL)
PMC
Number of CDI before FMT
Days from first CDI diagnosis to FMT
Days of last course of antibiotic treatment for CDI
Indication of FMT
Adverse events
1
83
Male
20
Alert
Impaired
Pneumonia
2
5
4,200
0.42
Yes
1
15
15
Refractory CDI
None
2∧
87
Male
20
Alert
Intact
Pneumonia
8
4
3,980
0.86
Yes
5
149
41
Refractory CDI
Vomiting
3
74
Male
10
Drowsy
Impaired
Pneumonia
14
10
5,200
2.57
Yes
2
29
10
Severe, complicated CDI
None
4
55
Male
20
Stupor
Impaired
Infectious colitis
3
5
6,240
0.68
No
5
486
37
Refractory CDI
None
5
75
Female
20
Alert
Intact
Urinary tract infection
3
5
18,830
2.3
No
4
459
7
Severe, complicated CDI
Vomiting
6
72
Male
20
Alert
Impaired
Pneumonia
6
4
12,350
0.97
Yes
2
237
27
Refractory CDI
None
7
83
Male
10
Sedated
Uncheckable
Pneumonia
1
5
8,440
0.64
Yes
1
37
37
Refractory CDI
None
FMT, fecal microbiota transplantation; K-P scale, Karnofsky Performance scale; CCIs, Charlson Comorbidity Index score; WBC, white blood cell; Cr, creatinine; PMC, pseudomembranous colitis; CDI, C. difficile infection. ∧Patients who had recurrence after FMT. Patient who received 2 sessions of FMT using colonoscopy before FMT using upper endoscopy.
