Research Article

Younger Age Is Associated with Poorer Survival in Patients with Signet-Ring Cell Carcinoma of the Colon without Distant Metastasis

Table 2

Univariate analyses of determinants of cancer-specific survival (CSS) of patients with nonmetastatic signet-ring cell carcinoma of the colon.

Variable5-year CSSLog rank value

Sex0.4660.495
 Male51.5%
 Female53.4%
Years of diagnosis1.8010.180
 1988–200350.5%
 2004–201153.7%
Race3.1690.205
 White53.7%
 Black43.4%
50.2%
Pathology grade1.5030.138
 Well/moderate58.4%
 Poor/undifferentiated52.5%
LNH0.1680.682
 ≤1851.2%
 >1853.5%
Tumor size (cm)1.8160.178
 ≤4.054.8%
 >4.051.9%
Primary site3.8590.049
 Right colon54.9%
 Left colon43.3%
Age at diagnosis (year)13.121<0.001
 ≤3531.1%
 >3554.9%
N stage148.599<0.001
 N088.3%
 N161.2%
 N230.0%
T stage63.528<0.001
 T190.4%
 T284.1%
 T359.8%
 T430.2%

LNH: number of lymph nodes harvested.
Includes Native American, Asian, Pacific Islander, and unknown.