Research Article
Younger Age Is Associated with Poorer Survival in Patients with Signet-Ring Cell Carcinoma of the Colon without Distant Metastasis
Table 2
Univariate analyses of determinants of cancer-specific survival (CSS) of patients with nonmetastatic signet-ring cell carcinoma of the colon.
| Variable | 5-year CSS | Log rank | value |
| Sex | | 0.466 | 0.495 | Male | 51.5% | | | Female | 53.4% | | | Years of diagnosis | | 1.801 | 0.180 | 1988–2003 | 50.5% | | | 2004–2011 | 53.7% | | | Race | | 3.169 | 0.205 | White | 53.7% | | | Black | 43.4% | | | | 50.2% | | | Pathology grade | | 1.503 | 0.138 | Well/moderate | 58.4% | | | Poor/undifferentiated | 52.5% | | | LNH | | 0.168 | 0.682 | ≤18 | 51.2% | | | >18 | 53.5% | | | Tumor size (cm) | | 1.816 | 0.178 | ≤4.0 | 54.8% | | | >4.0 | 51.9% | | | Primary site | | 3.859 | 0.049 | Right colon | 54.9% | | | Left colon | 43.3% | | | Age at diagnosis (year) | | 13.121 | <0.001 | ≤35 | 31.1% | | | >35 | 54.9% | | | N stage | | 148.599 | <0.001 | N0 | 88.3% | | | N1 | 61.2% | | | N2 | 30.0% | | | T stage | | 63.528 | <0.001 | T1 | 90.4% | | | T2 | 84.1% | | | T3 | 59.8% | | | T4 | 30.2% | | |
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LNH: number of lymph nodes harvested. Includes Native American, Asian, Pacific Islander, and unknown.
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