Younger Age Is Associated with Poorer Survival in Patients with Signet-Ring Cell Carcinoma of the Colon without Distant Metastasis

Table 3

Multivariate analyses of determinants of cancer-specific survival (CSS) of patients with nonmetastatic signet-ring cell carcinoma of the colon.

Variables	Multivariate analysis
	HR	95% CI	value
Primary site			0.696
Right colon	1	Reference
Left colon	0.950	0.732–1.231
Age at diagnosis (year)			0.031
>35	1	Reference
≤35	1.411	1.032–1.929
N stage			<0.001
N0	1	Reference
N1	2.977	1.840–4.817	<0.001
N2	6.392	4.102–9.961	<0.001
T stage			<0.001
T1	1	Reference
T2	1.406	0.257–7.707	0.695
T3	2.458	0.602–10.042	0.210
T4	3.988	0.970–16.391	0.055

HR: hazard ratio; CI: confidence interval.